EXPERIMENTAL PROTOCOL FOR DETECTING HIGHER ALCOHOL CONSUMERS FROM A CONVENTIONAL RAT LINE BASED ON BASAL ANXIETY

Experimental protocol for detecting higher alcohol consumers from a conventional rat line based on basal anxiety

Predisposition for a high alcohol intake and the impact of alcohol-abstinence-relapse may be reliable experimentally performed in conventional adult rat lines if animals received juvenile exposure to alcohol (e.g., by forced consumption) and selecting those individuals with high basal anxiety levels during juvenile periods.Importantly, a forced alc

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Biotechnological tools for genetic improvement of Trichoderma

Trichoderma is a cosmopolitan fungus widely distributed around the world.The different uses of this beneficial fungus are varied in several industries, like agriculture, textile, and paper, including the pharmaceutical industry.The genus Trichoderma has other mechanisms of action, including the production of different enzymes and secreted secondary

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The MicroRNA Landscape of Acute Beta Cell Destruction in Type 1 Diabetic Recipients of Intraportal Islet Grafts

Ongoing beta cell death in type 1 diabetes (T1D) can be detected using biomarkers selectively discharged by dying beta cells into plasma.microRNA-375 (miR-375) ranks among the top biomarkers based on studies in animal models and human islet transplantation.Our objective was to identify additional microRNAs that are co-released with miR-375 proporti

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